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Threshold Dynamics of a Vector-Borne Epidemic Model for Huanglongbing with Impulsive Control  [PDF]
Jianping Wang, Feifei Feng, Zhicai Guo, Hengmin Lv, Juanjuan Wang
Applied Mathematics (AM) , 2019, DOI: 10.4236/am.2019.104015
Abstract: In this paper, the basic reproduction number is calculated for Huanglongbing (HLB) model with impulses which is a vector-borne epidemic model with impulses. For controlling HLB, farmers’ experience is replanting of healthy plants and removing infected plants. To reflect the real world, we construct an impulsive control model which considers replanting of healthy plants and removing infected plants at one fixed time. By analyzing the model, we conclude that the disease-free equilibrium is globally asymptotically stable if the basic reproduction number Ro < 1, and we prove that the HLB is permanence if the basic reproduction number R
The Vulnerability Analysis of Some Typical Hash-Based RFID Authentication Protocols  [PDF]
Zhicai Shi, Shitao Ren, Fei Wu, Changzhi Wang
Journal of Computer and Communications (JCC) , 2016, DOI: 10.4236/jcc.2016.48001
Abstract: The low-cost RFID tags have very limited computing and storage resources and this makes it difficult to completely solve their security and privacy problems. Lightweight authentication is considered as one of the most effective methods to ensure the security in the RFID system. Many light-weight authentication protocols use Hash function and pseudorandom generator to ensure the anonymity and confidential communication of the RFID system. But these protocols do not provide?such security as they claimed. By analyzing some typical Hash-based RFID authentication protocols, it is found that they are vulnerable to some common attacks. Many protocols cannot resist tracing attack and de-synchronization attack. Some protocols cannot provide forward security. Gy?z? Gódor and Sándor Imre proposed a Hash-based authentication protocol and they claimed their protocol could resist the well-known attacks. But by constructing some different attack scenarios, their protocol is shown to be vulnerable to tracing attack and de-synchronization attack. Based on the analysis for the Hash-based authentication protocols, some feasible suggestions are proposed to improve the security of the RFID authentication protocols.
Pulse Roguing Strategy in a Pine Wilt Disease Epidemic Model with General Nonlinear Incidence Rate  [PDF]
Quanben Sun, Wugui Chen, Zhicai Guo, Weiwei Ji, Jianping Wang
Journal of Applied Mathematics and Physics (JAMP) , 2020, DOI: 10.4236/jamp.2020.812217
Abstract: In this study, we investigate a pine wilt transmission model with general nonlinear incidence rates and time-varying pulse roguing. Using the stroboscopic map and comparison theorem, we proved that the disease-free equilibrium is global attractive determined by the basic reproduction number R1 < 1, and in such a case, the endemic equilibrium does not exist. The disease uniformly persists only if R2 > 1.
Relationship between toxicity and molecular volume of dioxins, organic phosphorous compounds and n-alkanols
Zunyao Wang,Xiangyun Han,Liansheng Wang,Zhicai Zhai
Chinese Science Bulletin , 2004, DOI: 10.1360/03wb0173
Abstract: The molecular volumes of dioxins, organic phosphorous compounds and n-alkanols were computed at the B3LYP/6-311G** level, and were then correlated with their toxicity. It was surprisingly found that there exists the so-called “critical volume of toxicity” (CVT) in each series of compound of the present study, i.e. the toxicity increases with increase of the molecular volume when less than CVT, while decreasing with increase of the molecular volume when larger than CVT. The CVT for the three series of compounds is quite similar, ranging 0.309–0.320 nm3. It was proposed that the ordinary linear solvation energy relationship (LSER) should be modified with respect to the new findings, and accordingly the anaesthetic potency of partial fluorinated n-alkanols was predicted.
Effect of dietary vanadium on small intestinal morphology in broilers  [PDF]
Kangping Wang, Hengmin Cui, Xi Peng, Zhicai Zuo, Jing Fang, Junliang Deng, Yuanxin Deng, Wei Cui, Bangyuan Wu
Health (Health) , 2012, DOI: 10.4236/health.2012.49105
Abstract: The objective of this study was to determine the effects of dietary vanadium on small intestinal morphology of broilers by the methods of light microscopy (LM) and transmission electron microscopy (TEM). A total of 420 one-day-old avian broilers were divided into six groups (seven replicates in each group and ten broilers in each replicate) and fed on a control diet or the same diet supplemented with 5, 15, 30, 45 and 60 mg/kg vanadium in the form of ammonium metavanadate for 42 days. In comparison with those in the control group, the intestinal villus heights were decreased (P < 0.05 or P < 0.01) in the 30, 45 and 60 mg/kg groups, and crypt depths and villus height/crypt depth ratio were decreased in the 45 and 60 mg/kg groups. Ultrastructurally, the microvilli were apparently sparse and short, and the numbers of lysosomes were increased in abovementioned three intestines in the 45 and 60 mg/kg groups at 42 days of age. In conclusion, dietary vanadium in excess of 30 mg/kg could alter the villus height, crypt depth, villus height/crypt depth ratio and ultrastructure, which might impact the development of small intestines in broilers.
When NiO@Ni Meets WS2 Nanosheet Array: A Highly Efficient and Ultrastable Electrocatalyst for Overall Water Splitting
Ce Han,Dewen Wang,Qun Li,Zhicai Xing
- , 2018, DOI: 10.1021/acscentsci.7b00502
Abstract:
Cloning of a NaCl-induced fructose-1, 6-diphosphate aldolase cDNA fromDunaliella salina and its expression in tobacco
Xiaoning Zhang,Changfa Lin,Huoying Chen,Hao Wang,Zhicai Qu,Hongwei Zhang,Jianhong Yao,Daleng Shen
Science China Life Sciences , 2003, DOI: 10.1007/BF03182684
Abstract: Using Rapid Amplification of cDNA ends (RACE) technique, the full-length cDNA encoding a NaCl-induced fructose-1, 6-diphosphate aldolase (DsALDP) was obtained. It was shown that the DsALDP had a relatively high homology (66%–73%) to chloroplast fructose-1, 6-diphosphate aldolase (AldP) in many plants according to their amino acid sequences. The phylogenetic analysis further confirmed that AldP in alga is the nearest to DsALDP. As to its expression pattern,DsALDP was denovo synthesized by NaCl induction. Its expression level was significantly changed with inducing time. After the selectedDsALDP cDNA subcloned into a binary vector pBI121, the new construct was introduced into tobacco byAgrobacterium tumefaciens. The results of Southern blot and RT-PCR analysis of four transgenic T1 plants indicated thatDsALDP was integrated into genome of these transgenic plants and effectively expressed. Aldolase activities have been detected in T1-1, T1-2 and T1-3 plants by bioassay under 100–200 mmol/L NaCl. It was also observed that proline contents in them were differentially increased.
Cytokine and Chemokine Microarray Profiles in Lung and Hilar Nodes from Pigs after Experimental Infection with Actinobacillus Pleuropneumoniae
Zhicai Zuo,Hengmin Cui,Xi Peng,Junliang Deng,Jing Fang,Ya Wang,Zhihua Ren
Journal of Animal and Veterinary Advances , 2012, DOI: 10.3923/javaa.2012.4603.4610
Abstract: The objective of this study was to determine cytokine and chemokine microarray profiles in lung and Hilar Nodes (HN) from pigs infected with Actinobacillus Pleuropneumoniae (APP). Twenty pigs were randomly assigned to one of two groups: Control Group (CG) and inoculated with APP (TG). The infected-APP pigs lung exhibited significantly (p<0.05) greater levels of chemokines CCL2, CCL20, IL8 and slightly increase levels of chemokines CCL4, CCL5 and CXCL2 while significantly(p<0.05) decrease levels of chemokines CXCL10 and CXCL12. APP infection significantly (p<0.05 or 0.01) stimulated expression of cytokines IL-18, IL-6, TNF, GM-CSF, CASP3, CASP8 and significantly (p< 0.05 or 0.01) suppressed expression of cytokines CD40, IRF1 in lung. Cytokines in infected-APP pigs lung, IL-1A, IL-27, IRF3, IL-10 were slightly increased and CASP1, IRF7, IL-12B, IL-2 were slightly decreased. Relative cytokine and chemokine microarray data in HN indicated that APP infection significantly (p<0.05) stimulated expression of cytokine IL-6 and significantly (p<0.05 or 0.01) suppressed expression of cytokines CXCL12, CD40 and CASP1. In conclusion, 26 cytokine and chemokines mRNA expression levels in lung and HN obtained from infected-APP or control swines were elucidated in this study. This research provided evidence that the increased severity of lesions in the infected-APP swines was associated mainly with alterations of cytokine and chemokines microarray profiles, especialy in lung. The changes of all the cytokines in lung and HN can lead stem cells to produce granulocytes (neutrophils, eosinophils and basophils) and monocytes and also promoted neutrophil and macrophages to phagocytose bacterial and foreign antigen at the site of inflammation. Defense function of pig infection with APP was enhanced while immune function was weakened.
The Arabidopsis IDD14, IDD15, and IDD16 Cooperatively Regulate Lateral Organ Morphogenesis and Gravitropism by Promoting Auxin Biosynthesis and Transport
Dayong Cui,Jingbo Zhao,Yanjun Jing,Mingzhu Fan,Jing Liu,Zhicai Wang,Wei Xin,Yuxin Hu
PLOS Genetics , 2013, DOI: 10.1371/journal.pgen.1003759
Abstract: The plant hormone auxin plays a critical role in regulating various aspects of plant growth and development, and the spatial accumulation of auxin within organs, which is primarily attributable to local auxin biosynthesis and polar transport, is largely responsible for lateral organ morphogenesis and the establishment of plant architecture. Here, we show that three Arabidopsis INDETERMINATE DOMAIN (IDD) transcription factors, IDD14, IDD15, and IDD16, cooperatively regulate auxin biosynthesis and transport and thus aerial organ morphogenesis and gravitropic responses. Gain-of-function of each IDD gene in Arabidopsis results in small and transversally down-curled leaves, whereas loss-of-function of these IDD genes causes pleiotropic phenotypes in aerial organs and defects in gravitropic responses, including altered leaf shape, flower development, fertility, and plant architecture. Further analyses indicate that these IDD genes regulate spatial auxin accumulation by directly targeting YUCCA5 (YUC5), TRYPTOPHAN AMINOTRANSFERASE of ARABIDOPSIS1 (TAA1), and PIN-FORMED1 (PIN1) to promote auxin biosynthesis and transport. Moreover, mutation or ectopic expression of YUC suppresses the organ morphogenic phenotype and partially restores the gravitropic responses in gain- or loss-of-function idd mutants, respectively. Taken together, our results reveal that a subfamily of IDD transcription factors plays a critical role in the regulation of spatial auxin accumulation, thereby controlling organ morphogenesis and gravitropic responses in plants.
An Efficient Algorithm for Computing Attractors of Synchronous And Asynchronous Boolean Networks
Desheng Zheng, Guowu Yang, Xiaoyu Li, Zhicai Wang, Feng Liu, Lei He
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0060593
Abstract: Biological networks, such as genetic regulatory networks, often contain positive and negative feedback loops that settle down to dynamically stable patterns. Identifying these patterns, the so-called attractors, can provide important insights for biologists to understand the molecular mechanisms underlying many coordinated cellular processes such as cellular division, differentiation, and homeostasis. Both synchronous and asynchronous Boolean networks have been used to simulate genetic regulatory networks and identify their attractors. The common methods of computing attractors are that start with a randomly selected initial state and finish with exhaustive search of the state space of a network. However, the time complexity of these methods grows exponentially with respect to the number and length of attractors. Here, we build two algorithms to achieve the computation of attractors in synchronous and asynchronous Boolean networks. For the synchronous scenario, combing with iterative methods and reduced order binary decision diagrams (ROBDD), we propose an improved algorithm to compute attractors. For another algorithm, the attractors of synchronous Boolean networks are utilized in asynchronous Boolean translation functions to derive attractors of asynchronous scenario. The proposed algorithms are implemented in a procedure called geneFAtt. Compared to existing tools such as genYsis, geneFAtt is significantly faster in computing attractors for empirical experimental systems. Availability The software package is available at https://sites.google.com/site/desheng619?/download.
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